Ana amfani da acrylonitrile a cikin samar da filaye na acrylic, resins, da shafi na sama;a matsayin tsaka-tsaki a cikin samar da magunguna da dyes;a matsayin mai gyara polymer;kuma a matsayin fumigant.Yana iya faruwa a cikin iskar gas mai fitar da wuta saboda pyrolyses na kayan polyacrylonitrile.An gano cewa an saki Acrylonitrile daga acrylonitrile-styrene copolymer da acrylonitrile-styrene-butadiene copolymer kwalabe lokacin da waɗannan kwalabe suka cika da abubuwan sarrafa abinci kamar ruwa, 4% acetic acid, 20% ethanol, da heptane kuma an adana su har tsawon kwanaki 10. zuwa watanni 5 (Nakazawa et al. 1984).Sakin ya fi girma tare da ƙara yawan zafin jiki kuma an danganta shi da ragowar acrylonitrile monomer a cikin kayan polymeric.

Acrylonitrile wani danyen abu ne da ake amfani dashi don haɗa nau'ikan zaruruwan roba da yawa kamar su Dralon da acrylic fibers.Ana kuma amfani dashi azaman maganin kwari.

Kerarre na acrylic zaruruwa.A cikin robobi, kayan kwalliyar ƙasa, da masana'antar adhesives.A matsayin tsaka-tsakin sinadarai a cikin kira na antioxidants, Pharmaceuticals, dyes, surface-active agents, da dai sauransu A cikin kwayoyin halitta don gabatar da ƙungiyar cyanoethyl.A matsayin mai gyara ga polymers na halitta.A matsayin fumigant mai kashe kwari don adana hatsi.Gwaji don haifar da adrenal hemorrhagic necrosis a cikin berayen.